bis(4-fluorophenyl)(methyl)(1H-1,2,4-triazol-1-ylmethyl)silane; 1-[[bis(4-fluorophenyl)(methyl)silyl]methyl]-1H-1,2,4-triazole 

1-[[bis(4-fluorophenyl)methylsilyl]methyl]-1H-1,2,4-triazole 

C₁₆H₁₅F₂N₃Si

White, odourless crystals.

53-55^oC

3.9×10^-2 mPa (25^oC, gas saturation method)

1.30

In water 45 (pH 7.8), 54 (pH 7.2), 900 (pH 1.1) (all in mg/l, 20^oC). Readily soluble (>2 kg/l) in many organic solvents.

Stable for more than 2 years under normal storage conditions. Stable to light, and to temperatures up to 310^oC.

2.7×10^-4 Pa m³ mol^-1 (pH 8, 25^oC, calc.)

3.74 (pH 7, 25

2.5, v. weak base 

Inhibits ergosterol biosynthesis (steroid demethylation inhibitor). 

Systemic fungicide with protective and curative action. Its resistance to wash-off, redistribution by rainfall and vapour phase activity are important components in its biological activity.

Broad spectrum, systemic, preventive and curative fungicide effective against many pathogens (Ascomycetes, Basidiomycetes and Deuteromycetes). It is recommended for use on many crops, such as: apples (Venturia inaequalis, Podosphaera leucotricha); peaches (Sphaerotheca pannosa, Monilia laxa); cereals (all major diseases); grapes (Uncinula necator, Guignardia bidwellii); sugar beet (Cercospora beticola, Erysiphe betae); maize (Helminthosporium turcicum); sunflowers (Phomopsis helianthi); oilseed rape (Pseudocercosporella capsellae, Pyrenopeziza brassicae); bananas (Mycosphaerella spp.).

FAO/WHO 74, 76 (see part 2 of the Bibliography). 

Acute oral LD₅₀ for male rats 1100, female rats 674 mg/kg.

Acute percutaneous LD₅₀ for rabbits >2000 mg/kg; a mild irritant to skin and eyes, but not a skin sensitiser.

LC₅₀ for male rats 27, female rats 3.7 mg/l air.

(2 y) for rats 10 mg/kg diet; (1 y) for dogs 5 mg/kg diet; (1.5 y) for mice 25 mg/kg diet.

(JMPR) 0.001 mg/kg b.w. [1995]. 

WHO (a.i.) III

R40| R61| Xn; R22| N; R51, R53 

Acute oral LD₅₀ for mallard ducks >1590 mg/kg.

LC₅₀ (96 h) for rainbow trout 1.2, bluegill sunfish 1.7 mg/l.

LC₅₀ (48 h) 3.4 mg/l.

Results of several different studies under varying environmental conditions indicate average DT₅₀ 95 d. 

Product analysis by glc with FID (CIPAC Handbook, 1998, H, 171);