sodium 2,6-bis(4,6-dimethoxypyrimidin-2-yloxy)benzoate

sodium 2,6-bis[(4,6-dimethoxy-2-pyrimidinyl)oxy]benzoate

C₁₉H₁₇N₄NaO₈

White powder.

223-224 ℃

5.05 ×10^-6 mPa (25 ℃)

Bulk density 0.0737 (20 ℃, CIPAC MT 3)

℃In water 73.3 g/l (25 ). In methanol 26.3, acetone 0.043 g/l (25 ℃)

Stable in water; DT50 >1 y (pH 7 & 9), 448 h (pH 4). Stable to light. Not decomposed after 14 d at 55 ℃.

3.12 ×10-11 Pa m³ mol^-1 (calc.)

= -1.03 (23 ℃)

3.05

Branched chain amino acid synthesis (ALS or AHAS) inhibitor.

Selective, systemic post-emergence herbicide, absorbed by foliage and roots.

Control of grasses, sedges and broad-leaved weeds, especially Echinochloa spp., in direct-seeded rice, at rates of 15-45 g/ha. Also used to stunt growth of weeds in non-crop situations.

Acute oral LD₅₀ for male rats 4111, female rats 2635, male and female mice 3524 mg/kg.

Acute percutaneous LD₅₀ for rats >2000 mg/kg. Non-irritating to skin; slightly irritating to eyes (rabbits). 

LC₅₀ (4 h) for rats >4.48 mg/l

(2 y) for male rats 20 mg/kg diet (1.1 mg/kg b.w. daily), female rats 20 mg/kg diet (1.4 mg/kg b.w. daily), male mice 14.1 mg/kg daily, female mice 1.7 mg/kg b.w. daily.

0.011 mg/kg.

WHO (a.i.) U

Acute oral LD₅₀ for bobwhite quail >2250 mg/kg. Dietary LC₅₀ (5 d) for bobwhite quail and mallard ducks >5620 mg/kg diet.

Acute LC₅₀ (96 h) for rainbow trout and bluegill sunfish >100 ppm.

LC₅₀ (48 h) >100 ppm.

EC₅₀ (120 h) for Selenastrum capricornutum 3.4 mg/l, NOEC 0.625 mg/l.

NOEL (14 d) for Eisenia foetida >1000 mg/kg soil.

Following application to foliage and soil at 5-leaf stage of rice plants, c. 10% of carbon label was distributed between straw and roots at harvest.

>95% of dose applied to rats was excreted in urine and faeces within 7 d.

In soil, DT₅₀ <10 d (flooded and upland conditions).